It’s very disruptive in your life…the more
you try and control it, the worse it gets

Dyskinesia and OFF time disrupt daily life

Experiencing dyskinesia and OFF time throughout the day can affect activities of daily living and make it difficult for people to start and plan their day. Watch the impact on these Real GO GETTERS in the video below.

A closer look at dyskinesia and off time

The definition of dyskinesia is uncontrolled, involuntary, and unpredictable movements of the face, arms, legs, and/or torso.
They are often fluid and dance-like and may look like fidgeting or wriggling, but can affect each person differently.

OFF time is when medication, like levodopa, is wearing off or is not working optimally and PD symptoms (stiffness, slowness, tremors) return.


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Before taking GOCOVRI, tell your doctor about all medical conditions, including if you:

  • have kidney problems; unexpected sleepiness; take medicine to help you sleep or that makes you drowsy; have mental problems, such as suicidal thoughts, depression, or hallucinations; unusual urges including gambling, increased sex drive, compulsive eating, or shopping; or if you drink alcoholic beverages

  • are pregnant or plan to become pregnant or are breastfeeding or plan to breastfeed. GOCOVRI may harm your unborn baby and can pass into your breastmilk

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Especially tell your doctor if you take medicines like sodium bicarbonate.

What should I avoid while taking GOCOVRI?

  • Do not take GOCOVRI if you have severe kidney problems

  • Do not drive, operate machinery, or do other dangerous activities until you know how GOCOVRI affects you

  • Do not drink alcohol while taking GOCOVRI as it can increase your chances of serious side effects

  • Do not stop or change the dose of GOCOVRI before talking with your doctor. Call your healthcare provider if you have symptoms of withdrawal such as fever, confusion, or severe muscle stiffness

  • Do not take a flu nasal spray while taking GOCOVRI, but you can receive a flu shot

What are the possible side effects of GOCOVRI?

GOCOVRI may cause serious side effects, including:

  • falling asleep during normal activities, such as driving, talking, or eating, while taking GOCOVRI. You may fall asleep without being drowsy or warning. The risk is greater if you take GOCOVRI with medicines that cause drowsiness

  • suicidal thoughts or actions and depression

  • occurrence or worsening of hallucinations (seeing or hearing things that are not real)

  • feeling dizzy, faint or light headed, especially when you stand up too quickly, when first starting GOCOVRI, or if your dose has been increased

  • unusual urges including gambling, sexual, spending money, binge eating, and the inability to control them
    If you or your family notices that you are developing any new, unusual or sudden changes in behavior or related symptoms, tell your healthcare provider right away.

Be sure to take your medicine at bedtime as instructed. You may take GOCOVRI with or without food.

View the GOCOVRI Important Facts for additional Important Safety Information


Tap to see Important Safety Information

GOCOVRI® (amantadine) extended release capsules is a prescription medicine for treating dyskinesia (sudden uncontrolled movements) in Parkinson’s disease patients treated with levodopa therapy, with or without other medicines that increase the effects of dopamine in the brain. It is not known if GOCOVRI is safe and effective in children.


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