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Resources

Doctor Discussion Guide

Craft your discussion with our helpful guide. In PD, everybody's experience with dyskinesia is unique. These questions will help you and your doctor determine where you are and whether or not GOCOVRI may be right for you.

Care partners can also use the discussion guide to ask questions on their loved one's behalf.

Print the PDF, send a copy to your email, or save it to your desktop and get ready to talk about your dyskinesia, and if GOCOVRI may be right for you.


Dyskinesia Symptom Tracker

In PD, dyskinesia can affect your day-to-day activities. See how dyskinesia is affecting you and help your doctor understand its impact on your day-to-day life. Fill out the symptom tracker and bring it to your next visit.

Care partners can also use the symptom tracker to help their loved ones capture all the details about their dyskinesia.

You can save the symptom tracker to your desktop and fill it out each day when you check your email. You can also print the PDF and fill it out each day by hand.

Frequently Asked Questions

Tap the down arrow to read a list of commonly asked questions and answers about GOCOVRI.

GOCOVRI™ (amantadine) extended release capsules is a prescription medicine used for the treatment of dyskinesia (sudden uncontrolled movements) in people with Parkinson’s disease who are treated with levodopa therapy or levodopa therapy with other medicines that increase the effects of dopamine in the brain.

It is not known if GOCOVRI is safe and effective in children.

  • Do not take GOCOVRI if you have severe kidney problems
  • Do not drive, operate machinery, or do other dangerous activities until you know how GOCOVRI affects you
  • Do not drink alcohol while taking GOCOVRI. It can increase your chances of getting serious side effects
  • Tell your doctor if you have had or are planning to have a live flu (influenza) vaccination (nasal spray). You can receive the influenza vaccination shot but should not get a live influenza vaccine while taking GOCOVRI

To get GOCOVRI, you will need a prescription from your doctor. Once you have a prescription, your doctor will send your information to GOCOVRI Onboard™, a program that helps get your medicine to you. A Patient Care Coordinator will work with your health plan to take the necessary steps to get your prescription approved and filled and then arrange for the delivery of GOCOVRI.

The most common side effects of GOCOVRI include:
  • hallucinations
  • dizziness
  • dry mouth
  • swelling of legs and feet
  • constipation
  • falls

GOCOVRI may cause serious side effects, including:
  • Falling asleep during normal activities. You may fall asleep while doing normal activities such as driving a car, talking, or eating while taking GOCOVRI or other medicines that treat Parkinson’s disease. You may fall asleep without being drowsy or without warning. This may result in having accidents. Your chances of falling asleep while doing normal activities while taking GOCOVRI are greater if you take other medicines that cause drowsiness. Tell your doctor right away if this happens
  • Suicidal thoughts or actions and depression. Some people taking GOCOVRI have had suicidal thoughts, attempted suicide, or depression. Tell your doctor if you have new or sudden changes in mood, behaviors, thoughts, or feelings, including thoughts about hurting yourself or ending your life
  • Hallucinations. GOCOVRI can cause or worsen hallucinations (seeing or hearing things that are not real) or psychotic behavior. Contact your doctor if you have hallucinations
  • Feeling dizzy, faint, or lightheaded, especially when you stand up (orthostatic hypotension). Lightheadedness or fainting may happen when getting up too quickly from a sitting or lying position, especially after long periods of time, when first starting GOCOVRI or if your dose has been increased. Contact your doctor if you become lightheaded or faint when standing up
  • Unusual urges. Some people taking GOCOVRI get urges to behave in a way unusual for them. Examples of this are an unusual urge to gamble, increased sexual urges, strong urges to spend money, binge eating, and the inability to control these urges. If you notice or your family notices that you are developing any unusual behaviors, talk to your doctor

These are not all the possible side effects of GOCOVRI. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

You and your care partner should always tell your doctor about all of the medications you are taking. Your doctor will decide if you need to adjust any dosing.

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Especially tell your doctor if you:
  • take medicines like sodium bicarbonate
  • have had or are planning to have a live flu (influenza) vaccination (nasal spray). You can receive the influenza vaccination shot but should not get a live influenza vaccine while taking GOCOVRI

Know the medicines you take. Keep a list of them to show your doctor and pharmacist when you get a new medicine.

  • Take GOCOVRI exactly as your doctor tells you to
  • Start GOCOVRI with 1 capsule at bedtime. Your doctor may change your dose if needed. If your doctor tells you to take 2 capsules, take them together at bedtime
  • Do not stop or change GOCOVRI before talking with your doctor. Call your doctor if you have symptoms of withdrawal such as fever, confusion, or severe muscle stiffness
  • GOCOVRI may be taken with food or without food
  • Swallow GOCOVRI capsules whole. Do not crush, chew, or divide
  • GOCOVRI capsules may be opened and sprinkled on applesauce before swallowing. Sprinkle all of the medicine in the capsule on the applesauce. Take all of the medicine right away without chewing
  • If you miss a dose of GOCOVRI, do not take an extra dose. Take your usual dose of GOCOVRI on the next day at bedtime
  • If you have forgotten to take GOCOVRI for several days, contact your doctor
  • Do not drink alcohol with your dose of GOCOVRI
  • Do not use GOCOVRI capsules that are damaged or show signs of tampering
  • If you take too much GOCOVRI, call your doctor or go to the nearest hospital emergency room right away
  • Store GOCOVRI at room temperature between 68°F and 77°F (20°C to 25°C)
  • Keep GOCOVRI out of the reach of children
Take GOCOVRI as exactly as your doctor tells you to.
  • Start GOCOVRI with 1 capsule at bedtime. Your doctor may change your dose if needed. If your doctor tells you to take 2 capsules, take them together at bedtime
  • Do not stop or change GOCOVRI before talking with your doctor. Call your doctor if you have symptoms of withdrawal such as fever, confusion, or severe muscle stiffness

If you have renal impairment, you will need to adjust your GOCOVRI dosing. Do not take GOCOVRI if you have severe kidney problems. Your doctor will determine what is best for you.

If GOCOVRI is working, you and your care partner will likely notice less dyskinesia. You may also experience more functional time ("ON" time without troublesome dyskinesia) and less "OFF" time. Remember to check in regularly with your doctor about your progress. Learn more about how GOCOVRI helped people with PD in clinical trials here

"ON" Time "OFF" Time
When levodopa is working to control PD symptoms, but also the time when dyskinesia can happen
When your PD medicines are not working well or at all, resulting in PD symptoms such as:
  • slow movement
  • trouble standing or walking
  • feeling rigid and heavy
  • tremors

Functional time is "ON" time without troublesome dyskinesia. This is time when your PD symptoms are well controlled and you’re not experiencing dyskinesia.

Dyskinesia is caused by taking levodopa, an important medication used to treat PD. You may experience dyskinesia as sudden, involuntary, jerking, or twisting body movement. It may also look like fidgeting, wriggling, head bobbing, or body swaying.

Dyskinesia can affect the head, face, arms, legs, trunk, or the entire body. It can happen on both sides of the body or just one side.

Tremors are a symptom of PD. Tremors look like uncontrollable, back and forth shaking movements that most often affect the hands or feet when at rest. In the early stages of PD, many people will experience tremor on one side of the body. As the disease progresses, tremors often spread to the other side of the body but usually remains most noticeable on the side it originated on.

See how Ervin, an actual person with PD, describes what dyskinesia feels like to him.

Watch now

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Important Safety Information

Before taking GOCOVRI, tell your doctor about all medical conditions, including if you:

  • have kidney problems; unexpected sleepiness; take medicine to help you sleep or that makes you drowsy; have mental problems, such as suicidal thoughts, depression, or hallucinations; unusual urges including gambling, increased sex drive, compulsive eating, or shopping; or if you drink alcoholic beverages
  • are pregnant or plan to become pregnant or are breastfeeding or plan to breastfeed. GOCOVRI may harm your unborn baby and can pass into your breastmilk

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Especially tell your doctor if you take medicines like sodium bicarbonate.

What should I avoid while taking GOCOVRI?

  • Do not take GOCOVRI if you have severe kidney problems
  • Do not drive, operate machinery, or do other dangerous activities until you know how GOCOVRI affects you
  • Do not drink alcohol while taking GOCOVRI as it can increase your chances of serious side effects
  • Do not stop or change the dose of GOCOVRI before talking with your doctor. Call your healthcare provider if you have symptoms of withdrawal such as fever, confusion, or severe muscle stiffness
  • Do not take a flu nasal spray vaccine while taking GOCOVRI, but you can receive a flu shot

What are the possible side effects of GOCOVRI?

GOCOVRI may cause serious side effects, including:

  • falling asleep during normal activities, such as driving, talking, or eating, while taking GOCOVRI. You may fall asleep without being drowsy or warning. The risk is greater if you take GOCOVRI with medicines that cause drowsiness
  • suicidal thoughts or actions and depression
  • occurrence or worsening of hallucinations (seeing or hearing things that are not real)
  • feeling dizzy, faint or light headed, especially when you stand up too quickly, when first starting GOCOVRI, or if your dose has been increased
  • unusual urges including gambling, sexual, spending money, binge eating, and the inability to control them

If you or your family notices that you are developing any new, unusual or sudden changes in behavior or related symptoms, tell your healthcare provider right away.

The most common side effects of GOCOVRI include hallucination, dizziness, dry mouth, swelling of legs and feet, constipation, and falls.

Be sure to take your medicine at bedtime as instructed. You may take GOCOVRI with or without food.

Indication

What is GOCOVRI?

GOCOVRI™ (amantadine) extended release capsules is a prescription medicine for treating dyskinesia (sudden uncontrolled movements) in Parkinson’s disease patients treated with levodopa therapy, with or without other medicines that increase the effects of dopamine in the brain. It is not known if GOCOVRI is safe and effective in children.